Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium

Coronavirus disease 2019 (COVID-19) outcomes vary from asymptomatic infection to death. This disparity may reflect different airway levels of the SARS-CoV-2 receptor, ACE2, and the spike protein activator, TMPRSS2. Here we explore the role of genetics and co-expression networks in regulating these g...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:bioRxiv
Autores principales: Sajuthi, Satria P., DeFord, Peter, Jackson, Nathan D., Montgomery, Michael T., Everman, Jamie L., Rios, Cydney L., Pruesse, Elmar, Nolin, James D., Plender, Elizabeth G., Wechsler, Michael E., Mak, Angel CY, Eng, Celeste, Salazar, Sandra, Medina, Vivian, Wohlford, Eric M., Huntsman, Scott, Nickerson, Deborah A., Germer, Soren, Zody, Michael C., Abecasis, Gonçalo, Kang, Hyun Min, Rice, Kenneth M., Kumar, Rajesh, Oh, Sam, Rodriguez-Santana, Jose, Burchard, Esteban G., Seibold, Max A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239056/
https://ncbi.nlm.nih.gov/pubmed/32511326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.04.09.034454
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares