Biological Evaluation of Newly Synthesized Biaryl Guanidine Derivatives to Arrest β-Secretase Enzymatic Activity Involved in Alzheimer's Disease

Proteases BACE1 (β-secretases) enzymes have been recognized as a promising target associated with Alzheimer's disease (AD). This study was carried out on the principles of molecular docking, chemical synthesis, and enzymatic inhibition of BACE1 enzymes via biaryl guanidine-based ligands. Based...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Biomed Res Int
Main Authors: Ali, Sayyad, Asad, Muhammad Hassham Hassan Bin, Khan, Fahad, Murtaza, Ghulam, Rizvanov, Albert A., Iqbal, Jamshed, Babak, Borhan, Hussain, Izhar
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi 2020
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238388/
https://ncbi.nlm.nih.gov/pubmed/32462027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8934289
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים