Serum macrophage inhibitory cytokine-1 (MIC-1/GDF15): a potential screening tool for the prevention of colon cancer?

BACKGROUND: Macrophage inhibitory cytokine-1 (MIC-1/GDF15) mediates NSAID protection from colonic polyps in mice and is linked to the development of colorectal carcinoma in humans. Therefore, changes in serum MIC-1/GDF15 levels could predict the presence of pre-malignant colonic polyposis and assist...

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Udgivet i:Cancer Epidemiol Biomarkers Prev
Main Authors: Brown, David A., Hance, Kenneth W., Rogers, Connie J., Sansbury, Leah B., Albert, Paul S., Murphy, Gwen, Laiyemo, Adeyinka O, Wang, Zhuoqiao, Cross, Amanda J., Schatzkin, Arthur, Danta, Mark, Srasuebkul, Preeyaporn, Amin, Janaki, Law, Matthew, Breit, Samuel N., Lanza, Elaine
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238292/
https://ncbi.nlm.nih.gov/pubmed/22144502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0786
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