Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Gene Deletion Promotes Cancer Growth in TRAMP Prostate Cancer Prone Mice

The divergent TGF-β superfamily member, macrophage inhibitory cytokine-1 (MIC-1/GDF15), is overexpressed by most cancers, including prostate cancer (PCa). Whilst its circulating levels are linked to cancer outcome, the role MIC-1/GDF15 plays in cancer development and progression is incompletely unde...

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Publicado en:PLoS One
Autores principales: Husaini, Yasmin, Lockwood, Glen P., Nguyen, Trung V., Tsai, Vicky Wang-Wei, Mohammad, Mohammad G., Russell, Pamela J., Brown, David A., Breit, Samuel N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335046/
https://ncbi.nlm.nih.gov/pubmed/25695521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115189
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