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Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol(®) Enabled Amorphous Solid Dispersions
Abiraterone is a poorly water-soluble drug. It has a high melting point and limited solubility in organic solvents, making it difficult to formulate as an amorphous solid dispersion (ASD) with conventional technologies. KinetiSol(®) is a high-energy, fusion-based, solvent-free technology that can pr...
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| Gepubliceerd in: | Pharmaceutics |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7238130/ https://ncbi.nlm.nih.gov/pubmed/32295245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040357 |
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