Repurposed Analog of GLP-1 Ameliorates Hyperglycemia in Type 1 Diabetic Mice Through Pancreatic Cell Reprogramming

Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. An ideal immunotherapy should combine the blockade of the autoimmune response with the recovery of functional target cell mass. With the aim to develop new therapies for type 1 diabetes that could co...

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Détails bibliographiques
Publié dans:Front Endocrinol (Lausanne)
Auteurs principaux: Villalba, Adrian, Rodriguez-Fernandez, Silvia, Perna-Barrull, David, Ampudia, Rosa-Maria, Gomez-Muñoz, Laia, Pujol-Autonell, Irma, Aguilera, Eva, Coma, Mireia, Cano-Sarabia, Mary, Vázquez, Federico, Verdaguer, Joan, Vives-Pi, Marta
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Endocrinology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237704/
https://ncbi.nlm.nih.gov/pubmed/32477262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00258
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