Prenatal Betamethasone interferes with immune system development and alters target cells in autoimmune diabetes

Non-genetic factors are crucial in the pathogenesis of type 1 diabetes (T1D), a disease caused by autoimmunity against insulin-producing β-cells. Exposure to medications in the prenatal period may influence the immune system maturation, thus altering self-tolerance. Prenatal administration of betame...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Perna-Barrull, David, Rodriguez-Fernandez, Silvia, Pujol-Autonell, Irma, Gieras, Anna, Ampudia-Carrasco, Rosa M., Villalba, Adrian, Glau, Laura, Tolosa, Eva, Vives-Pi, Marta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362293/
https://ncbi.nlm.nih.gov/pubmed/30718757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37878-9
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