2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer

Despite the clinical success of Androgen Receptor (AR)-targeted therapies, reactivation of AR signalling remains the main driver of castration-resistant prostate cancer (CRPC) progression. In this study, we perform a comprehensive unbiased characterisation of LNCaP cells chronically exposed to multi...

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書誌詳細
出版年:Nat Commun
主要な著者: Blomme, Arnaud, Ford, Catriona A., Mui, Ernest, Patel, Rachana, Ntala, Chara, Jamieson, Lauren E., Planque, Mélanie, McGregor, Grace H., Peixoto, Paul, Hervouet, Eric, Nixon, Colin, Salji, Mark, Gaughan, Luke, Markert, Elke, Repiscak, Peter, Sumpton, David, Blanco, Giovanny Rodriguez, Lilla, Sergio, Kamphorst, Jurre J., Graham, Duncan, Faulds, Karen, MacKay, Gillian M., Fendt, Sarah-Maria, Zanivan, Sara, Leung, Hing Y.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237503/
https://ncbi.nlm.nih.gov/pubmed/32427840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16126-7
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