Co-Occurring Alterations of ERBB2 Exon 20 Insertion in Non-Small Cell Lung Cancer (NSCLC) and the Potential Indicator of Response to Afatinib

Background: Human epidermal growth factor receptor 2 (ERBB2, HER-2) exon 20 insertion (ERBB2ex20ins) remains a refractory oncogenic driver in lung cancer. So far there is limited data showing the co-occurring mutation background of ERBB2ex20ins in Chinese lung cancer and its relationship with respon...

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Veröffentlicht in:Front Oncol
Hauptverfasser: Yuan, Bo, Zhao, Jun, Zhou, Chengzhi, Wang, Xiumei, Zhu, Bo, Zhuo, Minglei, Dong, Xilin, Feng, Jiemei, Yi, Cuihua, Yang, Yunpeng, Zhang, Hua, Zhou, Wangyan, Chen, Zhengtang, Yang, Sheng, Ai, Xinghao, Chen, Kehe, Cui, Xuefan, Liu, Difa, Shi, Chunmei, Wu, Wei, Zhang, Yanjun, Chang, Lianpeng, Li, Jin, Chen, Rongrong, Yang, Shuanying
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236802/
https://ncbi.nlm.nih.gov/pubmed/32477948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00729
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