Clinical characterization of ERBB2 exon 20 insertions and heterogeneity of outcomes responding to afatinib in Chinese lung cancer patients

PURPOSE: ERBB2 exon 20 insertions (20ins) have been identified as oncogenic drivers in lung cancers. Lung cancer patients with 20ins benefit from afatinib. However, response heterogeneity was observed in patients harboring different 20ins subtypes. In this study, we interrogated clinical characteris...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Liu, Zhefeng, Wu, Lin, Cao, Jun, Yang, Zhe, Zhou, Chengzhi, Cao, Liming, Wu, Hao, Shen, Haibo, Jin, Meiling, Zhang, Yong, Mao, Xinru, Xiang, Jianxing, Ma, Ke, Li, Bing, Zhang, Tengfei, Hu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205822/
https://ncbi.nlm.nih.gov/pubmed/30425522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S173391
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