Benzofuran-Based Carboxylic Acids as Carbonic Anhydrase Inhibitors and Antiproliferative Agents against Breast Cancer

[Image: see text] Pursuing our effort for developing effective inhibitors of the cancer-related hCA IX isoform, here we describe the synthesis of novel benzofuran-based carboxylic acid derivatives, featuring the benzoic (9a–f) or hippuric (11a,b) acid moieties linked to 2-methylbenzofuran or 5-bromo...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Eldehna, Wagdy M., Nocentini, Alessio, Elsayed, Zainab M., Al-Warhi, Tarfah, Aljaeed, Nada, Alotaibi, Ohoud J., Al-Sanea, Mohammad M., Abdel-Aziz, Hatem A., Supuran, Claudiu T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236537/
https://ncbi.nlm.nih.gov/pubmed/32435420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00094
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