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[(18)F]ZCDD083: A PFKFB3-Targeted PET Tracer for Atherosclerotic Plaque Imaging
[Image: see text] PFKFB3, a glycolysis-related enzyme upregulated in inflammatory conditions and angiogenesis, is an emerging target for diagnosis and therapy of atherosclerosis. The fluorinated phenoxindazole [(18)F]ZCDD083 was synthesized, radiolabeled in 17 ± 5% radiochemical yield and >99% ra...
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| Udgivet i: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2020
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7236280/ https://ncbi.nlm.nih.gov/pubmed/32435408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00677 |
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