An immune cell signature of bacterial sepsis

Dysregulation of the immune response to bacterial infection can lead to sepsis, a condition with high mortality. Multiple whole-blood gene expression studies have defined sepsis-associated molecular signatures but did not resolve changes in transcriptional states of specific cell types. Here, we use...

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Udgivet i:Nat Med
Main Authors: Reyes, Miguel, Filbin, Michael R., Bhattacharyya, Roby P., Billman, Kianna, Eisenhaure, Thomas, Hung, Deborah T., Levy, Bruce D., Baron, Rebecca M., Blainey, Paul C., Goldberg, Marcia B., Hacohen, Nir
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235950/
https://ncbi.nlm.nih.gov/pubmed/32066974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-0752-4
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