1830. Single-cell Transcriptional Profiling Reveals an Immune Cell State Signature of Bacterial Sepsis

BACKGROUND: Despite intense efforts to understand the immunopathology of sepsis, no clinically reliable diagnostic biomarkers exist. Multiple whole-blood gene expression studies have sought sepsis-associated molecular signatures, but these have not yet resolved immune phenomena at the cellular level...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Reyes, Miguel, Bhattacharyya, Roby P, Filbin, Michael, Billman, Kianna, Eisenhaure, Thomas, Hung, Deborah T, Levy, Bruce, Baron, Rebecca, Blainey, Paul, Goldberg, Marcia B, Hacohen, Nir
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809350/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.092
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