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Two-Step Size-Exclusion Nanofiltration of Prothrombin Complex Concentrate Using Nanocellulose-Based Filter Paper

Coagulation Factor IX-rich protrhombin complex concentrate (FIX-PCC) is a therapeutic biologic product that consists of a mixture of several human plasma-derived proteins, useful for treating hemophilia B. Due to its complex composition, FIX-PCC is very challenging to bioprocess through virus removi...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Manukyan, Levon, Mantas, Athanasios, Razumikhin, Mikhail, Katalevsky, Andrey, Golubev, Eugen, Mihranyan, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235758/
https://ncbi.nlm.nih.gov/pubmed/32224972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8040069
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