Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

OBJECTIVE: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present study, we aimed to study the role of Beclin1 in li...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Son, Yeonho, Cho, Yoon Keun, Saha, Abhirup, Kwon, Hyun-Jung, Park, Ji-Hyun, Kim, Minsu, Jung, Young-Suk, Kim, Sang-Nam, Choi, Cheoljun, Seong, Je-Kyung, Burl, Rayanne B., Granneman, James G., Lee, Yun-Hee
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235646/
https://ncbi.nlm.nih.gov/pubmed/32344065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101005
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