Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

OBJECTIVE: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present study, we aimed to study the role of Beclin1 in li...

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Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Son, Yeonho, Cho, Yoon Keun, Saha, Abhirup, Kwon, Hyun-Jung, Park, Ji-Hyun, Kim, Minsu, Jung, Young-Suk, Kim, Sang-Nam, Choi, Cheoljun, Seong, Je-Kyung, Burl, Rayanne B., Granneman, James G., Lee, Yun-Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235646/
https://ncbi.nlm.nih.gov/pubmed/32344065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101005
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