Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, and incurable neurodegenerative disease. Recent studies suggest that dysregulation of gene expression by microRNAs (miRNAs) may play an important role in ALS pathogenesis. The reversible nature of this dysregulation makes miRNAs attractive...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Paez-Colasante, Ximena, Figueroa-Romero, Claudia, Rumora, Amy E., Hur, Junguk, Mendelson, Faye E., Hayes, John M., Backus, Carey, Taubman, Ghislaine F., Heinicke, Laurie, Walter, Nils G., Barmada, Sami J., Sakowski, Stacey A., Feldman, Eva L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235295/
https://ncbi.nlm.nih.gov/pubmed/32477070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00117
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