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RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages
Macrophages host Leishmania major infection, which causes cutaneous Leishmaniasis in humans. In the murine model, resistance to infection depends on the host immunity mediated by CD4 T-cell cytokines and macrophages. In association to other stimuli, the Th1 cytokine IFN-γ induces NO-mediated microbi...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7235166/ https://ncbi.nlm.nih.gov/pubmed/32477357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00886 |
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