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Selected arylsulphonyl pyrazole derivatives as potential Chk1 kinase ligands—computational investigations
Protein kinases control diversity of biochemical processes in human organism. Checkpoint 1 kinase (Chk1) is an important element of the checkpoint signalling pathways and is responsible for DNA damage repair. Hence, this kinase plays an essential role in cancer cells survival and has become an impor...
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| Опубликовано в: : | J Mol Model |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Berlin Heidelberg
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7235069/ https://ncbi.nlm.nih.gov/pubmed/32424505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-020-04407-3 |
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