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Selected arylsulphonyl pyrazole derivatives as potential Chk1 kinase ligands—computational investigations

Protein kinases control diversity of biochemical processes in human organism. Checkpoint 1 kinase (Chk1) is an important element of the checkpoint signalling pathways and is responsible for DNA damage repair. Hence, this kinase plays an essential role in cancer cells survival and has become an impor...

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Bibliografiske detaljer
Udgivet i:J Mol Model
Main Authors: Czaja, Kornelia, Kujawski, Jacek, Kamel, Karol, Bernard, Marek K.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235069/
https://ncbi.nlm.nih.gov/pubmed/32424505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-020-04407-3
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