The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice

Senotherapy targeting for senescent cells is designed to attenuate age-related dysfunction. Senescent T cells, defined as CD4(+) CD44(high) CD62L(low) PD-1(+) CD153(+) cells, accumulate in visceral adipose tissues (VAT) in obese individuals. Here, we show the long-lasting effect of using CD153 vacci...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Yoshida, Shota, Nakagami, Hironori, Hayashi, Hiroki, Ikeda, Yuka, Sun, Jiao, Tenma, Akiko, Tomioka, Hideki, Kawano, Tomohiro, Shimamura, Munehisa, Morishita, Ryuichi, Rakugi, Hiromi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7235045/
https://ncbi.nlm.nih.gov/pubmed/32424156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16347-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items