AJP001, a novel helper T‐cell epitope, induces a humoral immune response with activation of innate immunity when included in a peptide vaccine

Vaccine design requires well‐tailored formulations including a T‐cell epitope and adjuvants. We identified a novel cationic peptide, AJP001, which possesses a strong affinity for murine MHC class II alleles (H2‐IE(d) and H2‐IA(d)) and low affinity for H2‐IA(b). We designed an AJP001 and epitope pept...

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Detaylı Bibliyografya
Yayımlandı:FASEB Bioadv
Asıl Yazarlar: Tenma, Akiko, Nakagami, Hironori, Tomioka, Hideki, Sakaguchi, Makoto, Ide, Ryoko, Koriyama, Hiroshi, Hayashi, Hiroki, Shimamura, Munehisa, Rakugi, Hiromi, Morishita, Ryuichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996369/
https://ncbi.nlm.nih.gov/pubmed/32123820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00056
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