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Polygenic risk for Alzheimer's disease shapes hippocampal scene-selectivity
Preclinical models of Alzheimer’s disease (AD) suggest APOE modulates brain function in structures vulnerable to AD pathophysiology. However, genome-wide association studies now demonstrate that AD risk is shaped by a broader polygenic architecture, estimated via polygenic risk scoring (AD-PRS). Des...
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| Publicado no: | Neuropsychopharmacology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7234982/ https://ncbi.nlm.nih.gov/pubmed/31896120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0595-1 |
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