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Polygenic impact of common genetic risk loci for Alzheimer’s disease on cerebral blood flow in young individuals
Genome-wide association studies (GWAS) show that many common alleles confer risk for developing Alzheimer’s disease (AD). These risk loci may contribute to MRI alterations in young individuals, preceding the clinical manifestations of AD. Prior evidence identifies vascular dysregulation as the earli...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6345995/ https://ncbi.nlm.nih.gov/pubmed/30679549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36820-3 |
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