Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation and plasma lipids in the Health and Retirement Study.

Variants associated with modulation of c-reactive protein (CRP) and plasma lipids have been investigated for polygenic overlap with Alzheimer’s Disease risk variants. We examined pleiotropic genetic effects on cognitive impairment (CI) conditioned on genetic variants (SNPs) associated with systemic...

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Udgivet i:Neurobiol Aging
Main Authors: Lutz, Michael W., Casanova, Ramon, Saldana, Santiago, Kuchibhatla, Maragatha, Plassman, Brenda L., Hayden, Kathleen M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233428/
https://ncbi.nlm.nih.gov/pubmed/31201950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.10.028
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