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Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation and plasma lipids in the Health and Retirement Study.

Variants associated with modulation of c-reactive protein (CRP) and plasma lipids have been investigated for polygenic overlap with Alzheimer’s Disease risk variants. We examined pleiotropic genetic effects on cognitive impairment (CI) conditioned on genetic variants (SNPs) associated with systemic...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Lutz, Michael W., Casanova, Ramon, Saldana, Santiago, Kuchibhatla, Maragatha, Plassman, Brenda L., Hayden, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233428/
https://ncbi.nlm.nih.gov/pubmed/31201950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.10.028
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