Adherence and Population Pharmacokinetic Properties of Amodiaquine When Used for Seasonal Malaria Chemoprevention in African Children

Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC. Here, we evaluated the population pharmacokinetic properties of amodiaquine and its active metabolite, desethylamodiaquine, in children receiving SMC under directly observed ideal conditions (n...

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Publicat a:Clin Pharmacol Ther
Autors principals: Ding, Junjie, Coldiron, Matthew E., Assao, Bachir, Guindo, Ousmane, Blessborn, Daniel, Winterberg, Markus, Grais, Rebecca F., Koscalova, Alena, Langendorf, Celine, Tarning, Joel
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232861/
https://ncbi.nlm.nih.gov/pubmed/31652336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1707
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