Adherence and Population Pharmacokinetic Properties of Amodiaquine When Used for Seasonal Malaria Chemoprevention in African Children

Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC. Here, we evaluated the population pharmacokinetic properties of amodiaquine and its active metabolite, desethylamodiaquine, in children receiving SMC under directly observed ideal conditions (n...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Ding, Junjie, Coldiron, Matthew E., Assao, Bachir, Guindo, Ousmane, Blessborn, Daniel, Winterberg, Markus, Grais, Rebecca F., Koscalova, Alena, Langendorf, Celine, Tarning, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232861/
https://ncbi.nlm.nih.gov/pubmed/31652336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1707
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