Tracking Adeno-Associated Virus Capsid Evolution by High-Throughput Sequencing

Despite early successes using recombinant adeno-associated virus (rAAV) vectors in clinical gene therapy trials, limitations remain making additional advancements a necessity. Some of the challenges include variable levels of pre-existing neutralizing antibodies and poor transduction in specific tar...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Hum Gene Ther
Autori principali: de Alencastro, Gustavo, Pekrun, Katja, Valdmanis, Paul, Tiffany, Matthew, Xu, Jianpeng, Kay, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232707/
https://ncbi.nlm.nih.gov/pubmed/32024384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.339
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi