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Tracking Adeno-Associated Virus Capsid Evolution by High-Throughput Sequencing
Despite early successes using recombinant adeno-associated virus (rAAV) vectors in clinical gene therapy trials, limitations remain making additional advancements a necessity. Some of the challenges include variable levels of pre-existing neutralizing antibodies and poor transduction in specific tar...
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| Gepubliceerd in: | Hum Gene Ther |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Mary Ann Liebert, Inc., publishers
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7232707/ https://ncbi.nlm.nih.gov/pubmed/32024384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.339 |
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