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Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid

With the aim to explore the possibility to generate a zebrafish model of renal fibrosis, in this study the fibrogenic renal effect of aristolochic acid I (AAI) after immersion was assessed. This compound is highly nephrotoxic able to elicit renal fibrosis after exposure of rats and humans. Our resul...

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Détails bibliographiques
Publié dans:Toxins (Basel)
Auteurs principaux: Wang, Xixin, Giusti, Arianna, Ny, Annelii, de Witte, Peter A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232444/
https://ncbi.nlm.nih.gov/pubmed/32235450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12040217
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