Development and Application of Extraction Methods for LC-MS Quantification of Microcystins in Liver Tissue

A method was developed to extract and quantify microcystins (MCs) from mouse liver with limits of quantification (LOQs) lower than previously reported. MCs were extracted from 40-mg liver samples using 85:15 (v:v) CH(3)CN:H(2)O containing 200 mM ZnSO(4) and 1% formic acid. Solid-phase extraction wit...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Baliu-Rodriguez, David, Kucheriavaia, Daria, Palagama, Dilrukshika S. W., Lad, Apurva, O’Neill, Grace M., Birbeck, Johnna A., Kennedy, David J., Haller, Steven T., Westrick, Judy A., Isailovic, Dragan
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232250/
https://ncbi.nlm.nih.gov/pubmed/32325806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12040263
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