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Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity

The APOBEC3 family of cytidine deaminases are an important part of the host innate immune defense against endogenous retroelements and retroviruses like Human Immunodeficiency Virus (HIV). APOBEC3H (A3H) is the most polymorphic of the human APOBEC3 genes, with four major haplotypes circulating in th...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Chesarino, Nicholas M., Emerman, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232234/
https://ncbi.nlm.nih.gov/pubmed/32235597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12040378
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