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IGF1R Axis Inhibition Restores Dendritic Cell Antitumor Response in Ovarian Cancer

Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. The insulin-like growth factor (IGF) system plays a key role in regulating growth and invasiveness in several malignancies, including ovarian cancer. IGF1R targeting showed antiproliferative activity of EOC cells. However,...

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Détails bibliographiques
Publié dans:Transl Oncol
Auteurs principaux: Somri-Gannam, Lina, Meisel-Sharon, Shilhav, Hantisteanu, Shay, Groisman, Gabriel, Limonad, Ofer, Hallak, Mordechai, Bruchim, Ilan
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232112/
https://ncbi.nlm.nih.gov/pubmed/32428851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100790
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