Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells

Despite extensive mapping of long noncoding RNAs in immune cells, their function in vivo remains poorly understood. In this study, we identify over 100 long noncoding RNAs that are differentially expressed within 24 h of Th1 cell activation. Among those, we show that suppression of Malat1 is a hallm...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Hewitson, James P., West, Katie A., James, Kylie R., Rani, Gulab Fatima, Dey, Nidhi, Romano, Audrey, Brown, Najmeeyah, Teichmann, Sarah A., Kaye, Paul M., Lagos, Dimitris
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2020
Soggetti:
Immune Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231852/
https://ncbi.nlm.nih.gov/pubmed/32321759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900940
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