Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells

Despite extensive mapping of long noncoding RNAs in immune cells, their function in vivo remains poorly understood. In this study, we identify over 100 long noncoding RNAs that are differentially expressed within 24 h of Th1 cell activation. Among those, we show that suppression of Malat1 is a hallm...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Hewitson, James P., West, Katie A., James, Kylie R., Rani, Gulab Fatima, Dey, Nidhi, Romano, Audrey, Brown, Najmeeyah, Teichmann, Sarah A., Kaye, Paul M., Lagos, Dimitris
Format: Artigo
Idioma:Inglês
Publicat: AAI 2020
Matèries:
Immune Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231852/
https://ncbi.nlm.nih.gov/pubmed/32321759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900940
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