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miR‐132 suppresses transcription of ribosomal proteins to promote protective Th1 immunity

Determining the mechanisms that distinguish protective immunity from pathological chronic inflammation remains a fundamental challenge. miR‐132 has been shown to play largely immunoregulatory roles in immunity; however, its role in CD4(+) T cell function is poorly understood. Here, we show that CD4(...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Hewitson, James P, Shah, Kunal M, Brown, Najmeeyah, Grevitt, Paul, Hain, Sofia, Newling, Katherine, Sharp, Tyson V, Kaye, Paul M, Lagos, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446204/
https://ncbi.nlm.nih.gov/pubmed/30833344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846620
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