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Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity
This work aimed at improving the targeting and cytotoxicity of simvastatin (SMV) against colon cancer cells. SMV was encapsulated in chitosan polymers, followed by eudragit S100 microparticles. The release of SMV double coated microparticles was dependent on time and pH. At pH 7.4 maximum release wa...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Mar Drugs |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
MDPI
2020
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7231066/ https://ncbi.nlm.nih.gov/pubmed/32344610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18040226 |
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