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Effects of Cyclization on Activity and Stability of α-Conotoxin TxIB
α-Conotoxin TxIB specifically blocked α6/α3β2β3 acetylcholine receptors (nAChRs), and it could be a potential probe for studying addiction and other diseases related to α6/α3β2β3 nAChRs. However, as a peptide, TxIB may suffer from low stability, short half-life, and poor bioavailability. In this stu...
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| Опубликовано в: : | Mar Drugs |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7230940/ https://ncbi.nlm.nih.gov/pubmed/32235388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18040180 |
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