Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model

Targeting of G-quadruplexes, non-canonical conformations that form in G-rich regions of nucleic acids, has been proposed as a novel therapeutic strategy toward several diseases, including cancer and infections. The unavailability of highly selective molecules targeting a G-quadruplex of choice has h...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Tassinari, Martina, Zuffo, Michela, Nadai, Matteo, Pirota, Valentina, Sevilla Montalvo, Adriana Carolina, Doria, Filippo, Freccero, Mauro, Richter, Sara N
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Chemical Biology and Nucleic Acid Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229848/
https://ncbi.nlm.nih.gov/pubmed/32282912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa186
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge