A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids

[Image: see text] A copper complex embedded in the structure of a water-soluble naphthalene diimide has been designed to bind and cleave G-quadruplex DNA. We describe the properties of this ligand, including its catalytic activity in the generation of ROS. FRET melting, CD, NMR, gel sequencing, and...

Full description

Saved in:
Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Nadai, Matteo, Doria, Filippo, Scalabrin, Matteo, Pirota, Valentina, Grande, Vincenzo, Bergamaschi, Greta, Amendola, Valeria, Winnerdy, Fernaldo Richtia, Phan, Anh Tuân, Richter, Sara N., Freccero, Mauro
Format: Artigo
Language:Inglês
Published: American Chemical Society 2018
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242190/
https://ncbi.nlm.nih.gov/pubmed/30351011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05337
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items