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A Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic Acids
[Image: see text] A copper complex embedded in the structure of a water-soluble naphthalene diimide has been designed to bind and cleave G-quadruplex DNA. We describe the properties of this ligand, including its catalytic activity in the generation of ROS. FRET melting, CD, NMR, gel sequencing, and...
שמור ב:
| הוצא לאור ב: | J Am Chem Soc |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical
Society
2018
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6242190/ https://ncbi.nlm.nih.gov/pubmed/30351011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05337 |
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