Berberine Induces Autophagic Cell Death in Acute Lymphoblastic Leukemia by Inactivating AKT/mTORC1 Signaling

INTRODUCTION: Berberine has been reported to inhibit cancer cell growth by apoptosis induction and exhibits a protective role against cancer progression. The current study aims to investigate the effects of berberine on acute lymphoblastic leukemia (ALL) and the mechanism beyond apoptosis. METHODS:...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Liu, Jian, Liu, Peng, Xu, Tiantian, Chen, Zhiwei, Kong, Huimin, Chu, Weihong, Wang, Yingchao, Liu, Yufeng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229801/
https://ncbi.nlm.nih.gov/pubmed/32494123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S239247
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