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IL-33 promotes type 1 cytokine expression via p38 MAPK in human NK cells

This study tests the hypothesis that activation of MAPK by physiologically relevant concentrations of IL-33 contributes to enhanced cytokine expression by IL-12 stimulated human NK cells. While IL-33 canonically triggers type 2 cytokine responses, this cytokine can also synergize with type 1 cytokin...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Ochayon, David E., Ali, Ayad, Alarcon, Pablo C., Krishnamurthy, Durga, Kottyan, Leah C., Borchers, Michael T., Waggoner, Stephen N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229703/
https://ncbi.nlm.nih.gov/pubmed/32017227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A0120-379RR
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