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IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38α-dependent pathway

IL-4 and IL-13 are instrumental in the development and progression of allergy and atopic disease. Basophils represent a key source of these cytokines and produce IL-4 and IL-13 when stimulated with IL-18, a member of the IL-1 family of cytokines. Comparative analyses of the effects of caspase-1-depe...

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Detalhes bibliográficos
Main Authors: Kroeger, Kelly M., Sullivan, Brandon M., Locksley, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752018/
https://ncbi.nlm.nih.gov/pubmed/19451398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0708452
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