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Optical Control of Small Molecule–Induced Protein Degradation

As an emerging approach to protein perturbation, small molecule-induced protein degradation has gained significant attention as both a chemical tool and a potential therapeutic. To enable discreet control over its function, we have developed a broadly applicable approach for the optical activation o...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Naro, Yuta, Darrah, Kristie, Deiters, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229639/
https://ncbi.nlm.nih.gov/pubmed/31927988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b12718
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