Integration of transcriptome-wide association study and messenger RNA expression profile to identify genes associated with osteoarthritis

AIMS: Osteoarthritis (OA) is the most prevalent joint disease. However, the specific and definitive genetic mechanisms of OA are still unclear. METHODS: Tissue-related transcriptome-wide association studies (TWAS) of hip OA and knee OA were performed utilizing the genome-wide association study (GWAS...

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Gepubliceerd in:Bone Joint Res
Hoofdauteurs: Qi, Xin, Yu, Fangfang, Wen, Yan, Li, Ping, Cheng, Bolun, Ma, Mei, Cheng, Shiqiang, Zhang, Lu, Liang, Chujun, Liu, Li, Zhang, Feng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Arthritis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229301/
https://ncbi.nlm.nih.gov/pubmed/32435465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.93.BJR-2019-0137.R1
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