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CONNET: Accurate Genome Consensus in Assembling Nanopore Sequencing Data via Deep Learning

Single-molecule sequencing technologies produce much longer reads compared with next-generation sequencing, greatly improving the contiguity of de novo assembly of genomes. However, the relatively high error rates in long reads make it challenging to obtain high-quality assemblies. A computationally...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Zhang, Yifan, Liu, Chi-Man, Leung, Henry C.M., Luo, Ruibang, Lam, Tak-Wah
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229283/
https://ncbi.nlm.nih.gov/pubmed/32422594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101128
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