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Suppressed expression of LDHB promotes age-related hearing loss via aerobic glycolysis
Age-dependent decrease of mitochondrial energy production and cellular redox imbalance play significant roles in age-related hearing loss (ARHL). Lactate dehydrogenase B (LDHB) is a key glycolytic enzyme that catalyzes the interconversion of pyruvate and lactate. LDH activity and isoenzyme patterns...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7229204/ https://ncbi.nlm.nih.gov/pubmed/32415082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2577-y |
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