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Statistical Inference for Net Benefit Measures in Biomarker Validation Studies

Referral strategies based on risk scores and medical tests are commonly proposed. Direct assessment of their clinical utility requires implementing the strategy and is not possible in early phases of biomarker research. Prior to late-phase studies, net benefit measures can be used to assess the pote...

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Vydáno v:Biometrics
Hlavní autoři: Marsh, Tracey L., Janes, Holly, Pepe, Margaret S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228830/
https://ncbi.nlm.nih.gov/pubmed/31732971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.13190
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