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The activity of sulfono-γ-AApeptide helical foldamers that mimic GLP-1
Existing long α-helix mimicking necessitates the retention of most natural amino acid residues to maintain their biological activity. Here, we report the exploration of helical sulfono-γ-AApeptides with entire unnatural backbones for their ability to structurally and functionally mimic glucagon-like...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7228743/ https://ncbi.nlm.nih.gov/pubmed/32440547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz4988 |
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