The activity of sulfono-γ-AApeptide helical foldamers that mimic GLP-1

Existing long α-helix mimicking necessitates the retention of most natural amino acid residues to maintain their biological activity. Here, we report the exploration of helical sulfono-γ-AApeptides with entire unnatural backbones for their ability to structurally and functionally mimic glucagon-like...

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Bibliografische gegevens
Gepubliceerd in:Sci Adv
Hoofdauteurs: Sang, Peng, Zhou, Zhihong, Shi, Yan, Lee, Candy, Amso, Zaid, Huang, David, Odom, Timothy, Nguyen-Tran, Vân T.B., Shen, Weijun, Cai, Jianfeng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228743/
https://ncbi.nlm.nih.gov/pubmed/32440547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz4988
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