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Syndecan-1 Shedding Inhibition to Protect Against Ischemic Acute Kidney Injury Through HGF Target Signaling Pathway

BACKGROUND: The hepatocyte growth factor (HGF) target pathway plays pivotal renoprotective roles after acute kidney injury. Syndecan-1 (SDC-1) serves as the coreceptor for HGF. Shedding of SDC-1 is involved in various pathological processes. Thus, we hypothesized that ischemia/reperfusion injury ind...

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Bibliografiske detaljer
Udgivet i:Transplantation
Main Authors: Lu, Zhihui, Song, Nana, Shen, Bo, Xu, XiaLian, Fang, Yi, Shi, Yiqin, Ning, Yichun, Hu, Jiachang, Dai, Yan, Ding, Xiaoqiang, Zou, Jianzhou, Teng, Jie
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228646/
https://ncbi.nlm.nih.gov/pubmed/29557914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002170
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